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Low background and high contrast PET imaging of amyloid-β with [(11)C]AZD2995 and [(11)C]AZD2184 in Alzheimer’s disease patients
PURPOSE: The aim of this study was to evaluate AZD2995 side by side with AZD2184 as novel PET radioligands for imaging of amyloid-β in Alzheimer’s disease (AD). METHODS: In vitro binding of tritium-labelled AZD2995 and AZD2184 was studied and compared with that of the established amyloid-β PET radio...
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| 主要な著者: | , , , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Springer-Verlag
2013
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3590405/ https://ncbi.nlm.nih.gov/pubmed/23324871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-012-2322-6 |
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