Low background and high contrast PET imaging of amyloid-β with [(11)C]AZD2995 and [(11)C]AZD2184 in Alzheimer’s disease patients

PURPOSE: The aim of this study was to evaluate AZD2995 side by side with AZD2184 as novel PET radioligands for imaging of amyloid-β in Alzheimer’s disease (AD). METHODS: In vitro binding of tritium-labelled AZD2995 and AZD2184 was studied and compared with that of the established amyloid-β PET radio...

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Bibliografske podrobnosti
Main Authors: Forsberg, Anton, Juréus, Anders, Cselényi, Zsolt, Eriksdotter, Maria, Freund-Levi, Yvonne, Jeppsson, Fredrik, Swahn, Britt-Marie, Sandell, Johan, Julin, Per, Schou, Magnus, Andersson, Jan, Johnström, Peter, Varnäs, Katarina, Halldin, Christer, Farde, Lars, Svensson, Samuel
Format: Artigo
Jezik:Inglês
Izdano: Springer-Verlag 2013
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590405/
https://ncbi.nlm.nih.gov/pubmed/23324871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-012-2322-6
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