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The NLR protein, NLRX1, and its partner, TUFM, reduce type I interferon, and enhance autophagy

The NLR (nucleotide-binding domain leucine-rich repeat containing) proteins serve as regulators of inflammatory signaling pathways. NLRX1, a mitochondria-localized NLR protein, has been previously shown to negatively regulate inflammatory cytokine production activated via the MAVS-DDX58 (RIG-I) path...

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Detalhes bibliográficos
Main Authors: Lei, Yu, Wen, Haitao, Ting, Jenny P.Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590269/
https://ncbi.nlm.nih.gov/pubmed/23321557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.23026
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