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Amino acid regulation of autophagy through the GPCR TAS1R1-TAS1R3

Cells require the ability to rapidly detect decreases in concentrations of free amino acids so that homeostatic mechanisms, including autophagy, can be engaged to replenish amino acids. Amino acids are transported into cells where it is generally accepted that they are detected by an intracellular s...

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Bibliographic Details
Main Authors: Wauson, Eric M., Zaganjor, Elma, Cobb, Melanie H.
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590263/
https://ncbi.nlm.nih.gov/pubmed/23222068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.22911
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