Cyclooxygenase-2 Deficiency Enhances Th2 Immune Responses and Impairs Neutrophil Recruitment in Hepatic Ischemia/Reperfusion Injury

Cyclooxygenase-2 (COX-2) is a prostanoid-synthesizing enzyme that is critically implicated in a variety of pathophysiological processes. Using a COX-2-deficient mouse model, we present data that suggest that COX-2 has an active role in liver ischemia/reperfusion (I/R) injury. We demonstrate that COX...

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Hlavní autoři: Hamada, Takashi, Tsuchihashi, Seiichiro, Avanesyan, Armine, Duarte, Sergio, Moore, Carolina, Busuttil, Ronald W., Coito, Ana J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589995/
https://ncbi.nlm.nih.gov/pubmed/18209082
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