Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis

Aberrant T-cell activation underlies many autoimmune disorders, yet most attempts to induce T-cell tolerance have failed. Building on previous strategies for tolerance induction that exploited natural mechanisms for clearing apoptotic debris, we show that antigen-decorated microparticles (500-nm dia...

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Main Authors: Getts, Daniel R, Martin, Aaron J, McCarthy, Derrick P, Terry, Rachael L, Hunter, Zoe N, Yap, Woon Teck, Getts, Meghann Teague, Pleiss, Michael, Luo, Xunrong, King, Nicholas JC, Shea, Lonnie D, Miller, Stephen D
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589822/
https://ncbi.nlm.nih.gov/pubmed/23159881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2434
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