Therapeutic Inflammatory Monocyte Modulation Using Immune-Modifying Microparticles

Inflammatory monocyte-derived effector cells play an important role in the pathogenesis of numerous inflammatory diseases. However, no treatment option exists that is capable of modulating these cells specifically. We show that infused negatively charged, immune-modifying microparticles (IMPs), deri...

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Detalhes bibliográficos
Main Authors: Getts, Daniel R., Terry, Rachael L., Getts, Meghann Teague, Deffrasnes, Celine, Müller, Marcus, van Vreden, Caryn, Ashhurst, Thomas M., Chami, Belal, McCarthy, Derrick, Wu, Huiling, Ma, Jin, Martin, Aaron, Shae, Lonnie D., Witting, Paul, Kansas, Geoffrey S., Kühn, Joachim, Hafezi, Wali, Campbell, Iain L., Reilly, David, Say, Jana, Brown, Louise, White, Melanie Y., Cordwell, Stuart J., Chadban, Steven J., Thorp, Edward B., Bao, Shisan, Miller, Stephen D., King, Nicholas J. C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973033/
https://ncbi.nlm.nih.gov/pubmed/24431111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3007563
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