Therapeutic Inflammatory Monocyte Modulation Using Immune-Modifying Microparticles

Inflammatory monocyte-derived effector cells play an important role in the pathogenesis of numerous inflammatory diseases. However, no treatment option exists that is capable of modulating these cells specifically. We show that infused negatively charged, immune-modifying microparticles (IMPs), deri...

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Bibliographic Details
Main Authors: Getts, Daniel R., Terry, Rachael L., Getts, Meghann Teague, Deffrasnes, Celine, Müller, Marcus, van Vreden, Caryn, Ashhurst, Thomas M., Chami, Belal, McCarthy, Derrick, Wu, Huiling, Ma, Jin, Martin, Aaron, Shae, Lonnie D., Witting, Paul, Kansas, Geoffrey S., Kühn, Joachim, Hafezi, Wali, Campbell, Iain L., Reilly, David, Say, Jana, Brown, Louise, White, Melanie Y., Cordwell, Stuart J., Chadban, Steven J., Thorp, Edward B., Bao, Shisan, Miller, Stephen D., King, Nicholas J. C.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973033/
https://ncbi.nlm.nih.gov/pubmed/24431111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3007563
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