Therapeutic Inflammatory Monocyte Modulation Using Immune-Modifying Microparticles

Inflammatory monocyte-derived effector cells play an important role in the pathogenesis of numerous inflammatory diseases. However, no treatment option exists that is capable of modulating these cells specifically. We show that infused negatively charged, immune-modifying microparticles (IMPs), deri...

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Hlavní autoři: Getts, Daniel R., Terry, Rachael L., Getts, Meghann Teague, Deffrasnes, Celine, Müller, Marcus, van Vreden, Caryn, Ashhurst, Thomas M., Chami, Belal, McCarthy, Derrick, Wu, Huiling, Ma, Jin, Martin, Aaron, Shae, Lonnie D., Witting, Paul, Kansas, Geoffrey S., Kühn, Joachim, Hafezi, Wali, Campbell, Iain L., Reilly, David, Say, Jana, Brown, Louise, White, Melanie Y., Cordwell, Stuart J., Chadban, Steven J., Thorp, Edward B., Bao, Shisan, Miller, Stephen D., King, Nicholas J. C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973033/
https://ncbi.nlm.nih.gov/pubmed/24431111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3007563
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