Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis

Aberrant T-cell activation underlies many autoimmune disorders, yet most attempts to induce T-cell tolerance have failed. Building on previous strategies for tolerance induction that exploited natural mechanisms for clearing apoptotic debris, we show that antigen-decorated microparticles (500-nm dia...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Getts, Daniel R, Martin, Aaron J, McCarthy, Derrick P, Terry, Rachael L, Hunter, Zoe N, Yap, Woon Teck, Getts, Meghann Teague, Pleiss, Michael, Luo, Xunrong, King, Nicholas JC, Shea, Lonnie D, Miller, Stephen D
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589822/
https://ncbi.nlm.nih.gov/pubmed/23159881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2434
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk