Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53.
The E6 oncoproteins of the cancer-associated or high-risk human papillomaviruses (HPVs) target the cellular p53 protein. The association of E6 with p53 leads to the specific ubiquitination and degradation of p53 in vitro, suggesting a model by which E6 deregulates cell growth control by the eliminat...
Na minha lista:
| Udgivet i: | Mol Cell Biol |
|---|---|
| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
1993
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358960/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8380895/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.2.775-784.1993 |
| Tags: |
Ingen Tags, Vær først til at tagge denne postø!
|