Loading...
Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53.
The E6 oncoproteins of the cancer-associated or high-risk human papillomaviruses (HPVs) target the cellular p53 protein. The association of E6 with p53 leads to the specific ubiquitination and degradation of p53 in vitro, suggesting a model by which E6 deregulates cell growth control by the eliminat...
Saved in:
| Published in: | Mol Cell Biol |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Taylor & Francis
1993
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358960/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8380895/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.2.775 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|