Llwytho...

Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53.

The E6 oncoproteins of the cancer-associated or high-risk human papillomaviruses (HPVs) target the cellular p53 protein. The association of E6 with p53 leads to the specific ubiquitination and degradation of p53 in vitro, suggesting a model by which E6 deregulates cell growth control by the eliminat...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Huibregtse, J M, Scheffner, M, Howley, P M
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1993
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC358960/
https://ncbi.nlm.nih.gov/pubmed/8380895
Tagiau: Ychwanegu Tag
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