Spatial congregation of STAT binding directs selective nuclear architecture during T-cell functional differentiation

Higher-order genome organization shows tissue-specific patterns. However, functional relevance and the mechanisms shaping the genome architecture are poorly understood. Here we report a profound shift from promiscuous to highly selective genome organization that accompanies the effector lineage choi...

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Bibliografske podrobnosti
Main Authors: Hakim, Ofir, Sung, Myong-Hee, Nakayamada, Shingo, Voss, Ty C., Baek, Songjoon, Hager, Gordon L.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2013
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589535/
https://ncbi.nlm.nih.gov/pubmed/23212947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.147652.112
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