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Spatial congregation of STAT binding directs selective nuclear architecture during T-cell functional differentiation
Higher-order genome organization shows tissue-specific patterns. However, functional relevance and the mechanisms shaping the genome architecture are poorly understood. Here we report a profound shift from promiscuous to highly selective genome organization that accompanies the effector lineage choi...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cold Spring Harbor Laboratory Press
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3589535/ https://ncbi.nlm.nih.gov/pubmed/23212947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.147652.112 |
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