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5′ UTR Control of Native ERG and of Tmprss2:ERG Variants Activity in Prostate Cancer

ERG, a member of the ETS transcription factor family, is frequently overexpressed in prostate cancer as a result of its fusion to the androgen-responsive Tmprss2 gene. Different genomic rearrangements and alternative splicing events around the junction region lead to multiple combination of Tmprss2:...

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Bibliografiske detaljer
Main Authors: Zammarchi, Francesca, Boutsalis, George, Cartegni, Luca
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589450/
https://ncbi.nlm.nih.gov/pubmed/23472063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049721
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