TMPRSS2-ERG Fusion Prostate Cancer Heterogeneity: Clinical and Biologic Implications

OBJECTIVES: To characterize the clonality of TMPRSS2-ERG fusion in multifocal prostate cancer. METHODS: From 80 consecutive radical prostatectomy specimens, we identified 32 cases with multiple spatially separate tumors. In each case we assessed 2–3 tumor foci for TMPRSS2-ERG fusion using an ERG bre...

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Bibliografiske detaljer
Main Authors: Barry, Marc, Perner, Sven, Demichelis, Francesca, Rubin, Mark A.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198826/
https://ncbi.nlm.nih.gov/pubmed/17991527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.urology.2007.08.032
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