Molecular Characterization of TMPRSS2-ERG Gene Fusion in the NCI-H660 Prostate Cancer Cell Line: A New Perspective for an Old Model

Recent studies have established that a significant fraction of prostate cancers harbor a signature gene fusion between the 5′ region of androgen-regulated TMPRSS2 and an ETS family transcription factor, most commonly ERG. Studies on the molecular mechanisms and functional consequences of this import...

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Main Authors: Mertz, Kirsten D., Setlur, Sunita R., Dhanasekaran, Saravana M., Demichelis, Francesca, Perner, Sven, Tomlins, Scott, Tchinda, Joëlle, Laxman, Bharathi, Vessella, Robert L, Beroukhim, Rameen, Lee, Charles, Chinnaiyan, Arul M, Rubin, Mark A
Format: Artigo
Sprog:Inglês
Udgivet: Neoplasia Press Inc. 2007
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838578/
https://ncbi.nlm.nih.gov/pubmed/17401460
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