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Effects of Cyclic Intermittent Hypoxia on ET-1 Responsiveness and Endothelial Dysfunction of Pulmonary Arteries in Rats

Obstructive sleep apnoea (OSA) is a risk factor for cardiovascular disorders and in some cases is complication of pulmonary hypertension. We simulated OSA by exposing rats to cyclic intermittent hypoxia (CIH) to investigate its effect on pulmonary vascular endothelial dysfunction. Sprague-Dawley Rat...

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書誌詳細
主要な著者: Wang, Zhuo, Li, Ai-Ying, Guo, Qiu-Hong, Zhang, Jian-Ping, An, Qi, Guo, Ya-jing, Chu, Li, Weiss, J. Woodrow, Ji, En-Sheng
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589442/
https://ncbi.nlm.nih.gov/pubmed/23555567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058078
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