Changes in Innate and Permissive Immune Responses after HBV Transgenic Mouse Vaccination and lLong-Term-siRNA Treatment

BACKGROUND: Currently, no licensed therapy can thoroughly eradicate hepatitis B virus (HBV) from the body, including interferon α and inhibitors of HBV reverse-transcription. Small interfering RNA (siRNA) seem to be a promising tool for treating HBV, but had no effect on the pre-existing HBV covalen...

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Main Authors: Ren, Guang-Li, Huang, Guang-Yu, Zheng, Hong, Fang, Ying, Ma, Heng-Hao, Xu, Man-Chun, Zhang, Hong-Bin, Zhang, Wei-Yun, Zhao, Ya-Gang, Sun, Da-Yong, Hu, Wen-Kui, Liu, Jian
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589400/
https://ncbi.nlm.nih.gov/pubmed/23472088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057525
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