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Internalization Mechanisms of the Epidermal Growth Factor Receptor after Activation with Different Ligands

The epidermal growth factor receptor (EGFR) regulates normal growth and differentiation, but dysregulation of the receptor or one of the EGFR ligands is involved in the pathogenesis of many cancers. There are eight ligands for EGFR, however most of the research into trafficking of the receptor after...

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Détails bibliographiques
Auteurs principaux: Henriksen, Lasse, Grandal, Michael Vibo, Knudsen, Stine Louise Jeppe, van Deurs, Bo, Grøvdal, Lene Melsæther
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589378/
https://ncbi.nlm.nih.gov/pubmed/23472148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058148
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