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Replication and mutagenesis of UV-damaged DNA templates in human and monkey cell extracts.

We have used in vitro DNA replication systems from human HeLa cells and monkey CV-1 cells to replicate a UV-damaged simian virus 40-based shuttle vector plasmid, pZ189. We found that replication of the plasmid was inhibited in a UV fluence-dependent manner, but even at UV fluences which caused damag...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Carty, M P, Hauser, J, Levine, A S, Dixon, K
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 1993
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358932/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8417349/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.1.533
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