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Replication and mutagenesis of UV-damaged DNA templates in human and monkey cell extracts.

We have used in vitro DNA replication systems from human HeLa cells and monkey CV-1 cells to replicate a UV-damaged simian virus 40-based shuttle vector plasmid, pZ189. We found that replication of the plasmid was inhibited in a UV fluence-dependent manner, but even at UV fluences which caused damag...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Carty, M P, Hauser, J, Levine, A S, Dixon, K
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1993
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC358932/
https://ncbi.nlm.nih.gov/pubmed/8417349
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