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Oral Vaccination With Adeno-associated Virus Vectors Expressing the Neu Oncogene Inhibits the Growth of Murine Breast Cancer

Recombinant adeno-associated viruses (AAV) have been used for therapeutic gene transfer. These vectors offer a number of advantages including resistance to the effects of pH, a broad cellular tropism, efficient gene transfer, persistence of gene expression, and little toxicity. AAV vectors; however,...

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Main Authors: Steel, Jason C, Di Pasquale, Giovanni, Ramlogan, Charmaine A, Patel, Vyomesh, Chiorini, John A, Morris, John C
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589150/
https://ncbi.nlm.nih.gov/pubmed/23295951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.260
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