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Interleukin-15 and its Receptor Augment Dendritic Cell Vaccination Against the neu Oncogene Through the Induction of Antibodies Partially Independent of CD4-help
Interleukin-15 (IL-15) stimulates the differentiation and proliferation of T, B and NK cells, enhances CD8(+) cytolytic T cell activity, helps maintain CD44hiCD8(+) memory T cells, and stimulates immunoglobulin synthesis by B cells. IL-15 is trans-presented to effector cells by its receptor, IL-15Rα...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2818588/ https://ncbi.nlm.nih.gov/pubmed/20086176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-1301 |
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