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ATPase activity of human ABCG1 is stimulated by cholesterol and sphingomyelin

ATP-binding cassette protein G1 (ABCG1) is important for the formation of HDL. However, the biochemical properties of ABCG1 have not been reported, and the mechanism of how ABCG1 is involved in HDL formation remains unclear. We established a procedure to express and purify human ABCG1 using the susp...

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Autors principals: Hirayama, Hiroshi, Kimura, Yasuhisa, Kioka, Noriyuki, Matsuo, Michinori, Ueda, Kazumitsu
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3588875/
https://ncbi.nlm.nih.gov/pubmed/23172659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M033209
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