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Phospholipase D2 mediates signaling by ATPase class I type 8B membrane 1

Functional defects in ATPase class I type 8B membrane 1 (ATP8B1 or familial intrahepatic cholestasis 1, FIC1) lead to cholestasis by mechanism(s) that are not fully understood. One proposed pathophysiology involves aberrant signaling to the bile acid sensor, the farnesoid X receptor (FXR), via prote...

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Autores principales: Chen, Frank, Ghosh, Ayantika, Shneider, Benjamin L.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3588867/
https://ncbi.nlm.nih.gov/pubmed/23213138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M030304
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