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Phospholipase D2 mediates signaling by ATPase class I type 8B membrane 1
Functional defects in ATPase class I type 8B membrane 1 (ATP8B1 or familial intrahepatic cholestasis 1, FIC1) lead to cholestasis by mechanism(s) that are not fully understood. One proposed pathophysiology involves aberrant signaling to the bile acid sensor, the farnesoid X receptor (FXR), via prote...
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Autores principales: | , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
The American Society for Biochemistry and Molecular Biology
2013
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3588867/ https://ncbi.nlm.nih.gov/pubmed/23213138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M030304 |
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