A functional insulin-like growth factor I receptor is required for the mitogenic and transforming activities of the epidermal growth factor receptor.

When wild-type mouse embryo cells are stably transfected with a plasmid constitutively overexpressing the epidermal growth factor (EGF) receptor (EGFR), the resulting cells can grow in serum-free medium supplemented solely with EGF. Supplementation with EGF also induces in these cells the transforme...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Coppola, D, Ferber, A, Miura, M, Sell, C, D'Ambrosio, C, Rubin, R, Baserga, R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358831/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8007963/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.7.4588-4595.1994
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