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A functional insulin-like growth factor I receptor is required for the mitogenic and transforming activities of the epidermal growth factor receptor.

When wild-type mouse embryo cells are stably transfected with a plasmid constitutively overexpressing the epidermal growth factor (EGF) receptor (EGFR), the resulting cells can grow in serum-free medium supplemented solely with EGF. Supplementation with EGF also induces in these cells the transforme...

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Bibliografische gegevens
Hoofdauteurs: Coppola, D, Ferber, A, Miura, M, Sell, C, D'Ambrosio, C, Rubin, R, Baserga, R
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1994
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC358831/
https://ncbi.nlm.nih.gov/pubmed/8007963
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