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Enhancement or inhibition of insulin signaling by insulin receptor substrate 1 is cell context dependent.

Insulin treatment of Chinese hamster ovary (CHO) cells expressing high levels of the insulin receptor (CHO/IR cells) activates both c-fos serum response element and activator protein 1 (AP-1) reporter genes approximately 10-fold. In contrast, parental CHO cells display only two- to threefold insulin...

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Detalles Bibliográficos
Main Authors: Yamauchi, K, Pessin, J E
Formato: Artigo
Idioma:Inglês
Publicado: 1994
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC358814/
https://ncbi.nlm.nih.gov/pubmed/8007950
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