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Maintenance of Genomic Stability in Mouse Embryonic Stem Cells: Relevance in Aging and Disease

Recent studies have shown that mouse embryonic stem cells (mESCs) rely on a distinctive genome caretaking network. In this review, we will discuss how mESCs functionally respond to DNA damage and describe several modifications in mESC DNA damage response, which accommodate dynamic cycling and preser...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Giachino, Claudia, Orlando, Luca, Turinetto, Valentina
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3588006/
https://ncbi.nlm.nih.gov/pubmed/23358251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms14022617
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