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Maintenance of Genomic Stability in Mouse Embryonic Stem Cells: Relevance in Aging and Disease

Recent studies have shown that mouse embryonic stem cells (mESCs) rely on a distinctive genome caretaking network. In this review, we will discuss how mESCs functionally respond to DNA damage and describe several modifications in mESC DNA damage response, which accommodate dynamic cycling and preser...

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Autors principals: Giachino, Claudia, Orlando, Luca, Turinetto, Valentina
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3588006/
https://ncbi.nlm.nih.gov/pubmed/23358251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms14022617
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