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The WD40 protein Morg1 facilitates Par6–aPKC binding to Crb3 for apical identity in epithelial cells
Formation of apico-basal polarity in epithelial cells is crucial for both morphogenesis (e.g., cyst formation) and function (e.g., tight junction development). Atypical protein kinase C (aPKC), complexed with Par6, is considered to translocate to the apical membrane and function in epithelial cell p...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3587828/ https://ncbi.nlm.nih.gov/pubmed/23439680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201208150 |
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