The WD40 protein Morg1 facilitates Par6–aPKC binding to Crb3 for apical identity in epithelial cells

Formation of apico-basal polarity in epithelial cells is crucial for both morphogenesis (e.g., cyst formation) and function (e.g., tight junction development). Atypical protein kinase C (aPKC), complexed with Par6, is considered to translocate to the apical membrane and function in epithelial cell p...

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Main Authors: Hayase, Junya, Kamakura, Sachiko, Iwakiri, Yuko, Yamaguchi, Yoshihiro, Izaki, Tomoko, Ito, Takashi, Sumimoto, Hideki
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 2013
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Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587828/
https://ncbi.nlm.nih.gov/pubmed/23439680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201208150
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