Molecular Signatures of Human Induced Pluripotent Stem Cells Highlight Sex Differences and Cancer Genes

Although human induced pluripotent stem cells (hiPSCs) have enormous potential in regenerative medicine, their epigenetic variability suggests that some lines may not be suitable for human therapy. There are currently few benchmarks for assessing quality. Here we show that X-inactivation markers can...

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Detalhes bibliográficos
Main Authors: Anguera, Montserrat C., Sadreyev, Ruslan, Zhang, Zhaoqing, Szanto, Attila, Payer, Bernhard, Sheridan, Steven D., Kwok, Showming, Haggarty, Stephen J., Sur, Mriganka, Alvarez, Jason, Gimelbrant, Alexander, Mitalipova, Maisam, Kirby, James E., Lee, Jeannie T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587778/
https://ncbi.nlm.nih.gov/pubmed/22770242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2012.03.008
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