Analysis of the selectivity filter of the voltage-gated sodium channel Na(v)Rh

NaChBac is a bacterial voltage-gated sodium (Na(v)) channel that shows sequence similarity to voltage-gated calcium channels. To understand the ion-permeation mechanism of Na(v) channels, we combined molecular dynamics simulation, structural biology and electrophysiological approaches to investigate...

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Xu, Xia, Mengdie, Li, Yang, Liu, Huihui, Jiang, Xin, Ren, Wenlin, Wu, Jianping, DeCaen, Paul, Yu, Feng, Huang, Sheng, He, Jianhua, Clapham, David E, Yan, Nieng, Gong, Haipeng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587708/
https://ncbi.nlm.nih.gov/pubmed/23247626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2012.173
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