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Depletion of K-Ras promotes proteasome degradation of survivin
Mutant K-Ras and survivin both contribute to oncogenesis, but little is known about K-Ras requirement for the maintenance of the high levels of survivin in human tumors. Here we demonstrate that K-Ras depletion significantly decreases survivin levels in human cancer cells that harbor mutant but not...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Landes Bioscience
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3587453/ https://ncbi.nlm.nih.gov/pubmed/23324341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.23407 |
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