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Glucocorticoid receptor translational isoforms underlie maturational stage-specific glucocorticoid sensitivities of dendritic cells in mice and humans

Although glucocorticoids are a profoundly important class of anti-inflammatory and immunosuppressive agents, their actions in dendritic cells (DCs) are not well understood. We found that dexamethasone, a potent glucocorticoid, selectively induced apoptosis in mature, but not in immature, DCs in heal...

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Hlavní autoři: Cao, Yun, Bender, Ingrid K., Konstantinidis, Athanasios K., Shin, Soon Cheon, Jewell, Christine M., Cidlowski, John A., Schleimer, Robert P., Lu, Nick Z.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587320/
https://ncbi.nlm.nih.gov/pubmed/23297131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-05-432336
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