Glucocorticoid Receptor α Isoform-Selective Regulation of Antiapoptotic Genes in Osteosarcoma Cells: A New Mechanism for Glucocorticoid Resistance

Glucocorticoids regulate a variety of physiological processes and are commonly used to treat disorders of inflammation, autoimmune diseases, and cancer. Glucocorticoid action is predominantly mediated through the classic glucocorticoid receptor (GR)α isoform. Recent data suggest that the mature GRα...

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Detalhes bibliográficos
Main Authors: Gross, Katherine L., Oakley, Robert H., Scoltock, Alyson B., Jewell, Christine M., Cidlowski, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2011
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125093/
https://ncbi.nlm.nih.gov/pubmed/21527497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0051
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