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LPS regulates the expression of glucocorticoid receptor α and β isoforms and induces a selective glucocorticoid resistance in vitro

BACKGROUND: This study was aimed to evaluate the effect of LPS in glucocorticoid receptor (GR) isoforms expression on different cell lines and PBMC from healthy donors in vitro and glucocorticoid sensitivity of PBMC in vitro. METHODS: U-2 OS cell lines expressing GR isoforms, different cell lines (C...

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Detalhes bibliográficos
Publicado no:J Inflamm (Lond)
Main Authors: Molina, Maria Luisa, Guerrero, Julia, Cidlowski, John A., Gatica, Héctor, Goecke, Annelise
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5644185/
https://ncbi.nlm.nih.gov/pubmed/29075152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12950-017-0169-0
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