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LPS regulates the expression of glucocorticoid receptor α and β isoforms and induces a selective glucocorticoid resistance in vitro

BACKGROUND: This study was aimed to evaluate the effect of LPS in glucocorticoid receptor (GR) isoforms expression on different cell lines and PBMC from healthy donors in vitro and glucocorticoid sensitivity of PBMC in vitro. METHODS: U-2 OS cell lines expressing GR isoforms, different cell lines (C...

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Detalles Bibliográficos
Publicado en:J Inflamm (Lond)
Autores principales: Molina, Maria Luisa, Guerrero, Julia, Cidlowski, John A., Gatica, Héctor, Goecke, Annelise
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5644185/
https://ncbi.nlm.nih.gov/pubmed/29075152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12950-017-0169-0
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