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Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts.

Fibroblast cell lines, designated R- and W cells, were generated, respectively, from mouse embryos homozygous for a targeted disruption of the Igf1r gene, encoding the type 1 insulin-like growth factor receptor, and from their wild-type littermates. W cells grow normally in serum-free medium supplem...

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Publicado en:Mol Cell Biol
Main Authors: Sell, C, Dumenil, G, Deveaud, C, Miura, M, Coppola, D, DeAngelis, T, Rubin, R, Efstratiadis, A, Baserga, R
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 1994
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358728/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8196606/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.6.3604
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