Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts.

Fibroblast cell lines, designated R- and W cells, were generated, respectively, from mouse embryos homozygous for a targeted disruption of the Igf1r gene, encoding the type 1 insulin-like growth factor receptor, and from their wild-type littermates. W cells grow normally in serum-free medium supplem...

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Autores principales: Sell, C, Dumenil, G, Deveaud, C, Miura, M, Coppola, D, DeAngelis, T, Rubin, R, Efstratiadis, A, Baserga, R
Formato: Artigo
Lenguaje:Inglês
Publicado: 1994
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC358728/
https://ncbi.nlm.nih.gov/pubmed/8196606
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