Pharmacological modulation of circadian rhythms by synthetic activators of the deacetylase SIRT1

Circadian rhythms govern a wide variety of physiological and metabolic functions in many organisms, from prokaryotes to humans. We previously reported that silent information regulator 1 (SIRT1), a NAD(+)-dependent deacetylase, contributes to circadian control. In addition, SIRT1 activity is regulat...

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Hauptverfasser: Bellet, Marina M., Nakahata, Yasukazu, Boudjelal, Mohamed, Watts, Emma, Mossakowska, Danuta E., Edwards, Kenneth A., Cervantes, Marlene, Astarita, Giuseppe, Loh, Christine, Ellis, James L., Vlasuk, George P., Sassone-Corsi, Paolo
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2013
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587185/
https://ncbi.nlm.nih.gov/pubmed/23341587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1214266110
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