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Higher susceptibility to experimental autoimmune encephalomyelitis in Muc1-deficient mice is associated with increased Th1/Th17 responses

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system in which dendritic cells (DC) play an important role in the development of inflammatory responses. Recently it has been shown that Muc1, a membrane tethered glycoprotein, has an ability to suppress inflammatory responses...

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Bibliographic Details
Main Authors: Yen, Jui-Hung, Xu, Shuyun, Park, Yong Sung, Ganea, Doina, Kim, Kwang Chul
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587144/
https://ncbi.nlm.nih.gov/pubmed/23261777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2012.12.004
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