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Regulatory Light Chain Mutants Linked to Heart Disease Modify the Cardiac Myosin Lever-Arm
Myosin is the chemomechanical energy transducer in striated heart muscle. The myosin cross-bridge applies impulsive force to actin while consuming ATP chemical energy to propel myosin thick filaments relative to actin thin filaments in the fiber. Transduction begins with ATP hydrolysis in the cross-...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3587134/ https://ncbi.nlm.nih.gov/pubmed/23343568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi301500d |
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