Beta(3)-Adrenoreceptor Stimulation Ameliorates Myocardial Ischemia-Reperfusion Injury Via Endothelial Nitric Oxide Synthase and Neuronal Nitric Oxide Synthase Activation

OBJECTIVES: This paper examined whether nebivolol protects the heart via nitric oxide (NO) synthase and NO-dependent signaling in an in vivo model of acute myocardial infarction. BACKGROUND: Beta(3)-adrenergic receptor (AR) activation promotes endothelial nitric oxide synthase (eNOS) activity and NO...

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Main Authors: Aragón, Juan P., Condit, Marah E., Bhushan, Shashi, Predmore, Benjamin L., Patel, Sandeep S., Grinsfelder, D. Bennett, Gundewar, Susheel, Jha, Saurabh, Calvert, John W., Barouch, Lili A., Lavu, Madhav, Wright, Harold M., Lefer, David J.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586978/
https://ncbi.nlm.nih.gov/pubmed/22152956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2011.09.033
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