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Nitric oxide promotes distant organ protection: Evidence for an endocrine role of nitric oxide

Endothelial NOS (eNOS)-derived NO has long been considered a paracrine signaling molecule only capable of affecting nearby cells because of its short half-life in blood and relatively limited diffusion distance in tissues. To date, no studies have demonstrated that endogenously generated NO possesse...

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Autores principales: Elrod, John W., Calvert, John W., Gundewar, Susheel, Bryan, Nathan S., Lefer, David J.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516252/
https://ncbi.nlm.nih.gov/pubmed/18685092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800700105
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