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Calcium mishandling in diastolic dysfunction: mechanisms and potential therapies

Diastolic dysfunction is characterized by slow or incomplete relaxation of the ventricles during diastole, and is an important contributor to heart failure pathophysiology. Clinical symptoms include fatigue, shortness of breath, and pulmonary and peripheral edema, all contributing to decreased quali...

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Bibliographic Details
Main Authors: Asp, Michelle L., Martindale, Joshua J., Heinis, Frazer I., Wang, Wang, Metzger, Joseph M.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586938/
https://ncbi.nlm.nih.gov/pubmed/23022395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2012.09.007
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