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Focal but reversible diastolic sheet dysfunction reflects regional calcium mishandling in dystrophic mdx mouse hearts

Cardiac dysfunction is a primary cause of patient mortality in Duchenne muscular dystrophy, potentially related to elevated cytosolic calcium. However, the regional versus global functional consequences of cellular calcium mishandling have not been defined in the whole heart. Here we sought for the...

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Detalhes bibliográficos
Main Authors: Cheng, Ya-Jian, Lang, Di, Caruthers, Shelton D., Efimov, Igor R., Chen, Junjie, Wickline, Samuel A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468475/
https://ncbi.nlm.nih.gov/pubmed/22777417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00321.2012
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