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Unstabilized azomethine ylides for the stereoselective synthesis of substituted piperidines, tropanes and azabicyclo[3.1.0] systems

Acid treatment of densely substituted 2-silyl-1,2-dihydropyridines provides a new and convenient entry to reactive azomethine ylides that can (1) be protonated and reduced with high stereoselectivity to give piperidines, (2) participate in [3+2] dipolar cycloaddition to give tropanes, and (3) underg...

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Detaylı Bibliyografya
Asıl Yazarlar: Ischay, Michael A., Takase, Michael K., Bergman, Robert G., Ellman, Jonathan A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586708/
https://ncbi.nlm.nih.gov/pubmed/23398467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja312311k
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