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Recent Explosive Human Population Growth Has Resulted in an Excess of Rare Genetic Variants

Human populations have experienced recent explosive growth, expanding by at least three orders of magnitude over the past 400 generations. This departure from equilibrium skews patterns of genetic variation and distorts basic principles of population genetics. We characterized the empirical signatur...

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Detalhes bibliográficos
Main Authors: Keinan, Alon, Clark, Andrew G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586590/
https://ncbi.nlm.nih.gov/pubmed/22582263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1217283
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