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Deep resequencing reveals excess rare recent variants consistent with explosive population growth
Accurately determining the distribution of rare variants is an important goal of human genetics, but resequencing of a sample large enough for this purpose has been unfeasible until now. Here, we applied Sanger sequencing of genomic PCR amplicons to resequence the diabetes-associated genes KCNJ11 an...
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Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
Nature Publishing Group
2010
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3060603/ https://ncbi.nlm.nih.gov/pubmed/21119644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1130 |
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